All Ireland Infectious Diseases Study Database

Background

The All-Ireland Infectious Diseases cohort study (AIID Cohort), led by Prof Paddy Mallon is enrolling patients at a number of Irish Hospitals with infectious diseases, including Covid-19. The AIID Cohort is a multicentre, prospective, longitudinal, observational cohort that enrols consecutive adult subjects (over 18 years old) attending hospitals services for management of infections. The AIID Cohort recruits from eleven clinical centres across Ireland. Subjects provide consent for use of routine clinical and laboratory data for research. In addition, subjects' consent to collection and biobanking of biological samples, including respiratory samples such as nasopharyngeal swabs. The AIID Cohort is approved by local institutional review boards and all participants provide written, informed consent. Data and samples within the AIID Cohort are accessed through standardised Data Access Guidelines and all approved Data Access Requests are approved by the local Ethics Committee. The benefits of this study are to provide a flexible platform to respond to a quickly changing infectious disease states like the COVID-19 pandemic.

Data Description

The AIID Database captures harmonised clinical, demographic and laboratory information from participants enrolled across infectious disease services in Ireland. Data are collected through a structured Entry Data form that includes the following components:

1. Consent
The database records essential permissions regarding optional sample use, data sharing within and outside the EU/EEA, and future research use.

2. Demography
Demographic data capture key background characteristics required for clinical and epidemiological research.

3. Clinical Assessments
4. Biobanking
5. Medication
6. Test Results
7. Profiles
8. Questionnaires